In a single-blinded, randomized controlled trial involving young women with overweight/obesity and iron deficiency anemia, a weight loss intervention over three months led to significant reductions in body weight and improvements in iron status markers. The intervention group, who received tailored energy-restricted diets and individual consultation sessions with a dietitian, experienced notable increases in hemoglobin, serum ferritin, and serum iron. The intervention group also experienced decreases in high-sensitivity C-reactive protein and serum hepcidin level by the end of the trial.

These findings suggest that diet-induced weight loss can positively impact iron status and related clinical markers in young women with overweight/obesity and iron deficiency anemia. The study underscores the potential of tailored energy-restricted diets and individualized consultation sessions with a dietitian in improving both weight management and iron status among this population, highlighting the importance of holistic approaches to health interventions.

Reference: Alshwaiyat NM, Ahmad A, Al-Jamal HAN. Effect of diet-induced weight loss on iron status and its markers among young women with overweight/obesity and iron deficiency anemia: a randomized controlled trial. Front Nutr. 2023 May 22;10:1155947. doi: 10.3389/fnut.2023.1155947. PMID: 37284649; PMCID: PMC10240069.