Iron Supplementation Post-Gastric Bypass
A study aimed to evaluate whether iron supplementation after gastric bypass surgery meets the needs of both sexes. It also examined the potential for iron overload in men when using multivitamin supplements standardized for women. Conducted at a specialized academic outpatient center, the retrospective study spanned up to 36 months post-surgery and included 283 patients (71 men, 130 premenopausal women, and 82 postmenopausal women). The evaluation of iron status was based on serum ferritin concentrations.
Iron Deficiency Anemia in Pregnancy: New Insights
Iron deficiency anemia is the most common form of anemia globally. In the United States, routine screening for iron deficiency anemia occurs at the start of prenatal care, the third trimester, and before birth. Treatment typically involves oral iron supplementation, which can cause gastrointestinal side effects and reduce adherence. New evidence supports early screening before anemia onset and the use of intravenous iron to accelerate treatment. However, more research is needed on the effects of over-supplementation and iron deficiency without anemia to improve treatment protocols.
Efficient Anemia Supplements: What to Look For?
Anemia, a common condition, requires supplements that are effective, gentle on the stomach, and contain the right ingredients in the correct proportions. With numerous anemia supplements on the market making various claims, it’s important for consumers to identify which ones actually deliver results and are worth the money. Many products lack transparency about their ingredient dosages, leading to potential ineffectiveness. This has led to detailed guidelines on what to look for in a high-quality anemia supplement, emphasizing natural, easily digestible formulations.
Antenatal Anemia Linked to Higher Maternal Morbidity: US Cohort Study
This study aimed to assess the link between antenatally diagnosed anemia and severe maternal morbidity in a large US cohort. Using data from the Consortium on Safe Labor database, which included over 166,000 deliveries, women with antenatal anemia were compared to those without. The analysis revealed that women diagnosed with anemia during pregnancy had higher rates of severe maternal morbidity, neonatal adverse outcomes, and secondary outcomes such as maternal death, transfusion, cesarean delivery, and preterm delivery.
Study Challenges Race-Based Anemia Definitions in Pregnancy, Calls for Uniform Guidelines
This study investigated the effectiveness of race-based definitions for antepartum anemia in pregnant women. It focused on different hemoglobin (Hb) treatment thresholds for Black and non-Black women according to American College of Obstetricians and Gynecologists guidelines. By analyzing a cohort from the University of Pennsylvania, the study found that despite similar antepartum Hb levels, Black women had significantly increased odds of presenting with Hb<11g/dL at delivery compared to non-Black women.
Study Reveals Challenges in Treating Iron Deficiency Anemia in Autistic Children
Children with autism spectrum disorder (ASD) often encounter feeding difficulties, which can lead to various nutritional deficiencies, including iron deficiency anemia (IDA). These feeding problems are typically due to behavioral issues and food aversions common among children with ASD. Pediatric nurse practitioners play a crucial role in assessing these children for mineral deficiencies and need to be vigilant about the potential complexities in managing IDA in this population.
Diet Rich in Heme and Non-Heme Iron Enhances Treatment for Iron Deficiency Anemia
Incorporating specific foods into the diets of people with iron deficiency anemia can help increase red blood cell counts and hemoglobin levels. Foods rich in heme iron, such as meat, poultry, and fish, are highly effective as they are well absorbed by the body. Additionally, plant-based sources of non-heme iron, including dark green leafy vegetables, nuts, and legumes, also play a crucial role despite being less efficiently absorbed.
Review Reveals Ferric Maltol as Promising IDA Treatment for IBD and CKD Patients
A comprehensive review of the pharmacology, efficacy, and safety of ferric maltol (FM), an oral iron formulation, highlights its utility in treating iron deficiency anemia (IDA). Utilizing various sources like MEDLINE/PubMed, EMBASE, and other clinical data, this review focuses on English language literature assessing FM in IDA treatment, especially in patients with inflammatory bowel disease (IBD) and chronic kidney disease (CKD). FM stands out for its improved tolerability compared to other iron formulations, with phase 3 trials indicating significant benefits in anemia management and serum iron parameters.
Ferric Maltol in IBD Anemia Trial: Effective but Not Equivalent to IV Treatment
In a phase 3b trial comparing treatments for iron-deficiency anemia in inflammatory bowel disease, ferric maltol demonstrated clinical effectiveness but fell short of showing noninferiority to intravenous ferric carboxymaltose at week 12. Patients were randomized to receive either oral ferric maltol or intravenous ferric carboxymaltose, with the primary goal being to assess hemoglobin response rates. While ferric maltol showed significant hemoglobin increases, its responder rate was lower compared to ferric carboxymaltose (67% vs. 84% in intent-to-treat analysis).
Ferric Maltol Shows Promise in AEGIS-CKD Trial for CKD-Related Anemia
The AEGIS-CKD Phase 3 trial evaluated the effects of oral iron replacement therapy with ferric maltol in adults with stage 3 or 4 chronic kidney disease (CKD) and iron-deficiency anemia. The randomized, placebo-controlled trial, followed by an open-label extension at 30 US centers, involved administering ferric maltol or placebo for 16 weeks, then switching all patients to ferric maltol for up to 36 additional weeks. The primary outcome was the change in hemoglobin levels at week 16, along with ferritin, transferrin saturation, and serum iron measurements.
